Amyotrophic lateral sclerosis (ALS) is a motor neuron (MN) disease associated with progressive muscle atrophy, paralysis, and eventually death.Growing evidence demonstrates that the pathological process leading to ALS is the result of multiple altered mechanisms occurring not only in MNs but also in other Boys Hooded Flannel cell types inside and o
Natural Killer (NK) cells are important components of the immune system in the defense against tumor growth and metastasis.They release exosomes containing proteins and nucleic acids, including microRNAs (miRNAs).NK-derived exosomes play a role in the anti-tumor NK cell function since they are able to recognize and kill cancer cells.However, the in
We have generated MLi005-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a male patient with dominant dystrophic epidermolysis bullosa (DDEB).This iPSC line may be used as a model system for studies on skin Boys Hooded Flannel integrity, the extracellular matrix and skin barrier function.The characterization of t
Restless legs syndrome (RLS) is a common sleep-related neurological disorder that is characterized by the urge to move, worsening at rest, improvement with activity, and worsening in the evening and night.Dopamine agonists are usually the first-line therapy.Other agents including benzodiazepines, narcotics, and anticonvulsants have been used to tre
Abstract In the present work the authors report the result of their food ethnobotanical researches, which have been carried out BOW TIES in Sicily during the last thirty years.Data concerning 188 wild species used in the traditional Sicilian cuisine are reported.The authors underline those species that are partially or completely unknown for their